Synonyms:
a.k.a. gluten neuropathy
Diagnosis:
Diagnosis of Coeliac disease or serology positive for coeliac disease, plus clinical or electrodiagnostic neuropathy and exclusion of other causes
Clinical features:
Different patterns: sensorimotor neuropathy >mononeuropathy multiplex >motor neuropathy >small fibre neuropathy.
Findings on investigations:
+NCS/EMG:
- Axonal neuropathy pattern, different patterns (sensorimotor neuropathy >mononeuropathy multiplex >motor neuropathy >small fibre neuropathy)
Other tests:
- Associated with HLA-DQ2, HLA-DQ8
Pathology:
Epineurium: lymphocytic infiltrate. Endoneurium: lymphocytic infiltrate. Wallerian degeneration.