Vertebral Artery Stenosis, Extracranial

This section refers to extracranial vertebral artery stenosis due to atherosclerotic disease

Diagnosis:

Must exclude other etiologies of stroke: including intracranial atherosclerotic disease
Catheter angiography:

  • Gold standard test
  • Allows accurate determination of degree of stenosis and collateral pathways
  • Allows determination of intracranial disease

MRA
CTA
Ultrasound: is if insufficient sensitivity to exclude the diagnosis

Treatment:

Antiplatelet therapy and risk factor control in all patients with extracranial vertebral artery stenosis
Asymptomatic disease:

  • Very low stroke risk in asymptomatic disease on antiplatelet therapy

Address risk factors
Antiplatelets:

  • Aspirin with or dipyridamole
  • Or clopidogrel

Consider endovascular intervention (angioplasty +stenting):

  • Consider if failing medical therapy
  • Heparin during procedure
  • Aspirin +clopidogrel for 3 months

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