Diagnosis:
Clinical features plus supported investigations
Clinical features:
Acute onset. Lasts 1-24 hours.
Complete antrograde amnesia & limited retrograde amnesia (weeks or months).
May be disoriented to time, place but not to self.
Preserved cognitive functions apart from memory & disorientation
No decrease in level of consciousness. Able to interact appropriately during the episode
No other neurological features apart from: headache, dizziness,
No recent trauma or seizure
Findings on Investigations:
MRI:
- DWI: occasionally punctate hyperintensities in the hippocampus in dominant lobe or bilaterally.
- May be completely normal
SPECT: hypoperfusion in temporal lobe & hippocampus acutely. Resolves by 1 week.
EEG: normal
Treatment:
No is necessary. This is a self limited condition.