Primary Thunderclap Headache

Diagnosis:

Clinical +exclude secondary causes (see list below e.g. subarachnoid hemorrhage, venous sinus thrombosis & others):

  • Sudden onset, maximum intensity within 1 minute
  • Lasts 1hr to 10 days
  • Doesn’t recur within months

Note:

  • Secondary causes to exclude: SAH, intracranial hematoma, arterial dissection, venous sinus thrombosis, reversible cerebral vasoconstriction syndrome (RCVS),
  • Other primary headaches to exclude: primary headache associated with sexual activity, primary cough headache, primary exertional headache,

Investigations to consider:

CT: rule out SAH, intracranial hematoma, pituitary apoplexy, colloid cyst
Lumbar puncture if CT is negative: rule out SAH, Spontaneous intracranial hypotension SIH
Catheter angiography: Reversible cerebral vasoconstriction syndrome RCVS

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