Pineocytoma

Diagnosis:

Suggested by MRI and confirmed by pathology (brain biopsy/resection)

Clinical features:

Parinaud syndrome
Hydrocephalus

Findings on Investigations:

MRI:

  • Pineal region mass
  • Contrast enhancement

Pathology:

Histology:

  • Small round blue cell tumor. Rosettes may occur. Mitosis & necrosis are rare.

Immunohistochemistry: positive for= synaptophysin, NSE, neurofilament, Class III beta tubulin, chromogranin, retinal S antigen. Rarely GFAP positive

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