Diagnosis:
Suggested by MRI and confirmed by pathology (brain biopsy/resection)
Clinical features:
Parinaud syndrome
Hydrocephalus
Findings on Investigations:
MRI:
- Pineal region mass
- Contrast enhancement
Pathology:
Histology:
- Small round blue cell tumor. Rosettes may occur. Mitosis & necrosis are rare.
Immunohistochemistry: positive for= synaptophysin, NSE, neurofilament, Class III beta tubulin, chromogranin, retinal S antigen. Rarely GFAP positive