Periodic Limb Movements of Sleep

Diagnosis:

Is a polysomnographic diagnosis
Polysomnography:
=or > 15 episodes of periodic, stereotyped jerky movements of legs
Each movement: lasts 0.5-5 seconds in duration
Sequences of Movements are separated by 5-90 seconds. Measured from movement onset to movement onset.
These may occur in normal people and are not significant unless associated with arousals

Treatment:

  • Ropinirole (Level A strong evidence)
  • Pramipexole, rotigotine, cabergoline, or pregabalin (Level B moderate evidence)

Related articles:

Related articles:

  1. Winkelman JW, Armstrong MJ, Allen RP, Chaudhuri KR, Ondo W, Trenkwalder C, Zee PC, Gronseth GS, Gloss D, Zesiewicz T. Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2016 Nov 16. pii:. PMID:27856776DOI:10.1212/WNL.0000000000003388