Periodic Alternating Nystagmus PAN

Diagnosis:

Primary position of gaze: Horizontal jerk nystagmus to one direction for 2 minutes, this then changes/alternates to the opposite direction every 2 minutes
May be associated with Anti-GAD antibodies

Clinical features:

Oscillopsia
Nystagmus

Findings on investigations:

MRI: hemorrhage or stroke of the nodulus of the cerebellum, Chiari-Malformation, Arachnoid cyst, Multiple sclerosis
Anti-GAD antibody

Treatment:

Baclofen orally

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