Diagnosis:
Suggested by MRI and confirmed by pathology (brain biopsy/resection)
Pathology:
Histology:
- Spindle cell tumor, densely packed, fascicular appearance. Interstitial axons (sliver impregnation or neurofilament)
Immunohistochemistry: positive for= S100. Neurofilament positive interstitial axons.
Findings on Investigations:
Plexiform type is almost always associated with neurofibromatosis type I
MRI:
- Widened neural foramina. Erosion of the pedicle. Usually dorsal spinal nerve roots