Meningioma

Diagnosis:

Suggested by MRI and confirmed by pathology (brain biopsy/resection)

Findings on Investigations:

CT: hyperdense, uncommonly calcify,
MRI:

  • Extraaxial, parasagittal dura >convexities >sphenoid wing >cerebellopontine angle cistern >olfactory groove >plantum sphenoidale. May encase arteries. May invade bone (hyperostotic or osteolytic).
  • T1: hypointense, enhancement of lesion & dural tail. Vascular flow voids may occur.
  • T2: hypointense, with hyperintense CSF surrounding it ‘cleft sign’,

Catheter angiography: tumor blush and blood supply is noted.

Pathology:

Well circumscribed, attached to dura
Histology: monomorphic cells, round/oval nuclei, syncytium. psammoma bodies, whorls, capsule. Brain invasion defines WHO grade II meningioma
Immunohistochemistry: positive for vimentin, EMA. Negative for GFAP
Associated with neurofibromatosus type 2

Treatment:

Surgical excision
Consider preoperative Catheter angiography

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