Heavy Metal Neuropathy and Solvent Neuropathy

Diagnosis:

Neuropathy
+documented high heavy metal level
+improvement of symptoms/signs/NCS/EMG after withdrawal of agent

Clinical features:

Clinical features of neuropathy: may be motor neuropathy, sensori-motor polyneuropathy

Findings on investigations:

NCS/EMG:

  • Axonal pattern

Specific causes:

  • Lead neuropathy (see lead poisoning), Mercury (see mercury poisoning),
  • Others, arsenic, thallium, gold, N-Hexane inhalation

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