Eosinophilic Myositis and Eosinophilic Fasciitis

Eosinophilic myositis

Occurs in hypereosinophilic syndrome, parasitic infections, Churg Strauss syndrome,

Muscle biopsy:

  • Inflammatory cells including eosinophils

 

Eosinophilic fasciitis a.k.a. Shulman syndrome:

Clinical features:

Subcutaneous induration sparing the face and fingers
Stiff joints
FBC: raised eosinophils

Biopsy:

Scleroinflammatory lesions in the fascia, may extend into the dermis or muscle.
Well circumscribed or absent eosinophilia
Perivascular lymphocytes and plasma cells

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