Corticosteroid Myopathy

Synonyms:

Steroid induce myopathy

Diagnosis:

This is a clinical diagnosis supported by exclusion of other causes. Usually it does not require biopsy but often it is used in cases of uncertainty

Clinical features:

Proximal weakness, usually gradual onset

Findings on investigations:

+/-CK normal or reduced
+/-Muscle biopsy: Type 2 fibre atrophy, especially type 2B. Lipid and/or glycogen accumulation can occur. Vacuolar myopathy can occur.

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