Diagnosis:
Suggested by MRI and confirmed by pathology (brain biopsy/resection)
Findings on Investigations:
Posterior fossa > supratentorial
Pathology:
Histology:
- Small round blue cell tumor, with rhabdoid cells= eccentric nucleus with prominent nucleolus, eosinophilic cytoplasmic inclusions,
- Immunohistochemistry: INI1 negative (distinguishes it from choroid plexus carcinoma which is INI1 positive, but this is not a perfect test), EMA positive, smooth muscle actin positive, Cytokeratin positive, GFAP= positive