Astroblastoma

Diagnosis:

Suggested by MRI and confirmed by pathology (brain biopsy/resection)

Findings on Investigations:

MRI:

  • Usually cystic, intraaxial, well demarcatd
  • Enhancing

Pathology:

Histology: Oval nuclei, cytoplasm fibrillary or cuboidal
Perivascular pseudorosette with broad processes`. Vascular hyalinisation.
Immunohistochemistry: positive for GFAP, S100. Negative for Synaptophysin, neurofilament, NeuN, chromogranin

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