Diagnosis:
This is diagnosed by a combination of clinical features, imaging finding and sometimes associated laboratory tests
Clinical features:
Prodrome e.g. Upper respiratory tract infection
Then Headache
Then cerebellar ataxia
Then improvement
Findings on investigations:
MRI +GAD:
- Normal,
- Then cerebellar enhancement of folia & hemispheres, swelling of hemispheres, tonsillar ectopia
- Then mild cerebellar atrophy, resolution of enhancement & tonsillar ectopia
SPECT:
- Hyperperfusion of the cerebellum
CSF:
- Lymphocytosis, normal to mildly increased protein, normal glucose
Other tests:
- EBV serologies: positive in some cases
Treatment:
Consider plasmapheresis if persistent. [case reports]